If you’re asking: “Do I have to compensate for the doppler shift when I am making a radio contact with the ISS?”, the article I link below is for you.
Thanks to Ron Hashiro AH6RH
https://www.qsl.net/ah6rh/am-radio/spacecomm/doppler-and-the-iss.html
Compensating for Doppler Shift
Short, real-world answer: No! I turned my TX power down to 2W and spoke to an astronaut when he was about 600 miles downrange … http://work-sat.com/ISS-062814.html
Thank you for sharing Clint! This is a great QSO!